Critical - Use Choice (1)ritonavir will enhance the degree or effect of sildenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Steer clear of or Use Alternate Drug. If used concomitantly, monitor for toxicities. Patients obtaining indinavir with ritonavir ought to receive not a lot more than twenty five mg of sildenafil for treatment method of erectile dysfunction inside of a forty eight-hour time period, and clients obtaining other protease inhibitors ought to utilize a reduced Original sildenafil dose of 25 mg. Affected individual using sildenafil for PAH with ritonavir will not be recommended.
Keep track of blood pressure level reaction to sildenafil in clients receiving concurrent blood pressure lowering therapy.
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carbamazepine will decrease the level or effect of sildenafil by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Watch. Powerful CYP3A4 inducers are envisioned to trigger sizeable decreases in sildenafil plasma concentrations
These are definitely not all the attainable side effects of Viagra® and generic Viagra®. To find out more, check with your healthcare company or pharmacist.
Clients receiving indinavir with ritonavir really should acquire not a lot more than twenty five mg of sildenafil for remedy of erectile dysfunction in a 48-hour interval, and clients getting other protease inhibitors ought to make use of a decrease First sildenafil dose of 25 mg. Affected person taking sildenafil for PAH with ritonavir is not really encouraged.
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butabarbital will decrease the extent or effect of sildenafil by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Keep track of.
tobramycin inhaled and sildenafil each increase nephrotoxicity and/or ototoxicity. Modify Therapy/Observe Carefully. Keep away from concurrent or sequential use to decrease possibility for ototoxicity
sotalol boosts effects of sildenafil by additive vasodilation. Use Caution/Keep an eye on. Sildenafil has systemic vasodilatory properties and could even further reduce blood pressure level in people taking antihypertensive medications.
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amobarbital will lessen the level or effect of sildenafil by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Observe.
The effectiveness and security of sildenafil citrate inside the remedy of PAH secondary to sickle cell anemia has not been recognized.